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Am. J. Biomed. Sci. 2018,10(3),129-138;doi:10.5099/aj180300129
Received:09 April 2018; | Revised:03 June 2018; | Accepted: 24 August 2018

 

Applied Fluid-Structure Interaction Technique to Initial Insight into the Effect of Exercise on the Aortic Valve Stroke Work

 

Hamidreza Ghasemi Bahraseman1*, Ehsan Mohseni Languri2*, Morteza Mohssenzadeh1,

Seyed Javad Amirfakhri3, Hadi Shojaei4, Kamran Hassani5, Hossein Derakhshandeh6

 

1Mechanical Engineering Department, San Diego State University, San Diego, 92182, CA, USA

2Department of Mechanical Engineering, Tennessee Technological University, Cookeville, TN 38505, USA

3Mechanical Engineering Department, Cal Poly Pomona, Pomona, CA 91768, USA

4Department of Pathology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH 44106,USA

5Department of Biomechanics, Science and Research Branch, Islamic Azad University, Tehran, Iran

6Department of Mechanical & Material Engineering, University of Nebraska-Lincoln, Lincoln, NE 68588, USA

*Corresponding Author

1Hamidreza Ghasemi Bahraseman

Mechanical Engineering Department,

San Diego State University,

San Diego, 92182, CA, USA

Phone: (901) 567-8750

Fax: (931) 372-6340

Email:hghasemibahraseman@sdsu.edu

2Ehsan Mohseni Languri

Department of Mechanical Engineering,

Tennessee Technological University,

Cookeville, TN 38505, USA

Phone: (931) 372-6790

Fax: (931) 372-6340

Email:ELanguri@tntech.edu

 

Abstract

The left ventricular stroke work is a measure of the work done by the left ventricle during the ejection of blood throughout per cardiac cycle. The aim of this investigation was to propose a model to numerically evaluate the stroke work for a healthy subject using a fluid-structure interaction (FSI) simulation during exercise protocol. Aortic valve dimensions were calculated using an imaging technique of echocardiography. A FSI simulation was performed using an Arbitrary Lagrangian-Eulerian (ALE) mesh. Boundary conditions were defined by pressure loads on ventricular and aortic sides. Stroke work was predicted to increase to 121% from 60 bpm to 125 bpm, and it did not increase much above 125 bpm. Based on derived regression equations of our FSI results of stroke work and comparing them with clinical ones, numerically-predicted stroke work values are in good agreements with published clinical data. The slope of stroke work changes to mean arterial pressure, while exercise protocol, is 168.08 ml which is 12.2% less than the average slope of clinical data. The y-axis intercepted of stroke work changes to mean arterial pressure, while exercise protocol, is -11186 which is 15% less than the average y-axis intercept of clinical data. Our results of the specific patient show that numerical methods can be proposed to predict good estimates of patient specific stroke work at different heart rates.

 

Keywords:Aortic valve, Finite element method, Fluid solid interaction, Stroke work

 

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