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Am. J. Biomed. Sci. 2018,10(3),184-188;doi:10.5099/aj180300184
Received: 01 July 2018; | Revised:23 July 2018; | Accepted: 10 September 2018


Haptoglobin Phenotypes and Association with Vascular Complications in Nigerian Type 2 Diabetes Patients


1Olayinka Olaolu OLANIYAN,2Humphrey B OSADOLOR


1Department of Chemical Pathology,Osun State University, Osogbo, Osun State, Nigeria

2Department of Medical Laboratory Science,University of Benin, Benin, Edo State, Nigeria

*Corresponding Author

O.O. Olaniyan

Department of Chemical pathology

Osun State University



Cell Phone: +2348034766014




Haptoglobin phenotypes were determined in 120 type 2 diabetes mellitus (including 60 diabetics with vascular complications and 60 diabetics without any vascular complications) and were compared to 50 apparently healthy individuals. A higher frequency of Hp 2 allele gene and Hp 2-2 phenotype was observed in diabetics and diabetics with vascular complications respectively. We found an association between Hp 2 allele in type 2 diabetes mellitus and Hp 2-2 phenotypes in diabetics with vascular complications. Hence, we conclude that screening diabetics for Hp 2-2 phenotypes would be an added advantage in patient focus management.


Keywords: Haptoglobin phenotypes, Type 2 Diabetes, Vascular complications, Nigerian


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