S1Q3T3 Pattern or McGinn-White Sign: Prevalence and Distribution among Apparently Healthy Young Adult Nigerians

¹Department of Physiological Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria

²Department of Medical Pharmacology and Therapeutics, Obafemi Awolowo University,Ile-Ife, Nigeria

^*Corresponding Author

Oluwadare Ogunlade

Department of Physiological Sciences

College of Medicine and Health Sciences

Obafemi Awolowo University

Ile-Ife

Nigeria

Email: ogunladeomotomilayo@gmail.com

Abstract

Background:S1Q3T3 pattern or McGinn-White Sign is an uncommon but classical electrocardiographic feature of pulmonary embolism. This unique pattern is scarcely reported among healthy individuals.

Objective: This study aimed at determining the prevalence and distribution of S1Q3T3 pattern among apparently healthy young adult population.

Methodology: The study was conducted over a period of one year during which undergraduates within the age range of 15-40 years in a Tertiary Institution in Nigeria were recruited for the exercise as part of the medical screening procedure. The age and sex were obtained and resting standard 12-lead electrocardiogram (ECG) was recorded from each participant in a relaxed atmosphere according to standard protocol. The participants whose ECG exhibited S1Q3T3 pattern were identified using pattern recognition method. The data was analyzed using descriptive statistics.

Result: Out of total of three thousand eight hundred and fifty-eight (3858) young adults (1963 males and 1895 females) who participated in this study, 36 (14 males and 22 females) had S1Q3T3 pattern. The prevalence of S1Q3T3 pattern among apparently healthy young adults was 0.93%. More females (1.16%) were affected than males (0.71%).

Conclusion: The study concluded that S1Q3T3 pattern or McGinn-White sign though described as a classical electrocardiographic sign of pulmonary embolism may occur in apparently healthy young adult.

Keywords:S1Q3T3 pattern, McGinn-White sign, Prevalence, Distribution, Young adults

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