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Am. J. Biomed. Sci. 2020,12(1),14-26;doi:10.5099/aj200100014
Received:13 August 2019; | Revised:30 August 2019; | Accepted:04 March 2020


Assessment of Hepatitis B and Hepatitis C Virus Infections and Associated Risk Factors among Patients Attended Rwanda Military Hospital 


Ange Yvette Uwitonze1, Jean de Dieu Tuyishime1, Pacifique Ndishimye2, William Niyonzima4, Jean Marie Vianney Halleluia3, Callixte Yadufashije2*

1MSc,1 BSc, Department of Biomedical Laboratory Sciences, INES Ruhengeri-Institute of Applied Sciences, Rwanda

2PhD, Department of Biomedical Laboratory Sciences, INES Ruhengeri-Institute of Applied Sciences, Rwanda

3BSc, Rwanda Military Hospital

4BSc, Department of Biomedical Laboratory Sciences, INES Ruhengeri-Institute of Applied Sciences, Rwanda

*Corresponding Author

Dr. CallixteYadufashije

Department of Biomedical Laboratory Sciences and Directorate of Research and consultancy

INES Ruhengeri- Institute of Applied Sciences


Email: cyadufashije@ines.ac.rw, cyadufashije@gmail.com



Background:Viral hepatitis is an infection affecting the liver and causing its inflammation due to viruses mostly hepatitis B and C viruses. Hepatitis B and C virus infections are serious global health issue leading to morbidity and mortality worldwide. Hepatitis B and C virus can lead to liver damage, liver cirrhosis and liver carcinoma. These infections are serologically characterized by the presence of HCV-Ab and HBsAg in serum.

Objectives:The objective was to assess hepatitis B and C viral infections and associated risk factors among patients attended Rwanda Military Hospital.

Materials and methods: This was a cross sectional study and was carried out between September 2016 and November 2016.  A total of 100 participants were eligible in the research based on inclusion Criteria. HCV-Ab and HBsAg were detected using rapid diagnostic tests with immunochromatographic method and positive samples were confirmed using Cobas e411 analyzer, with electrochemiluminescence method. The results for Hepatitis B and C  were statistically analyzed using SPSS 16.0.

Results: The results of the present study show that hepatitis B and C infections prevalence were high and several risk factors for HCV and HBV were reported. The statistics show that HCV prevalence was higher than that of HBV with  20% and 17%  respectively. Age and marital status were the only significant risk factors for Hepatitis C (Age,x2=17.389, df=3, p=0.001, Marital status,x2=11.096, df=3  p= 0.01). The lack of vaccination against HBV was the only significant risk factor for HBV (x=4.496, df=1, p=0.034).

Conclusion: There was no Hepatitis B  and C co-infection among the patients.Several risk factors for hepatitis B and C were reported. Education of the population about HCV and HBV infections, screening and vaccination, were urgently recommended in order to prevent and cut down the HBV and HCV infections.


Keywords:Hepatitis B virus, Hepatitis C virus, Risk factors,Cirrhosis 


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